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Ingredient

Retinoids

Also called: Retinol, Retinaldehyde, Adapalene, Differin, Tretinoin, Retin-A

The best-studied night active for acne, texture, collagen support, and long-term skin quality.

Sharon’s verdict

Worth it

What Sharon would tell you

Retinoid is the umbrella term for vitamin A derivatives like retinol, retinaldehyde, adapalene, and tretinoin. This is the night active with the strongest long-term evidence.

Start slow, use a pea-sized amount, apply to dry skin, and moisturize. Adapalene is an excellent over-the-counter option. Tretinoin is prescription strength. Pregnant or nursing patients should skip retinoids.